General Information

  • ID:  hor000461
  • Uniprot ID:  E9GSK4
  • Protein name:  Allatostatin B2
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  AWSDLSQQGW
  • Length:  10(128-137)
  • Propeptide:  MQFWQCPLLLMVSLIAAINTQQTPSQRLEPNQVAGLVELHQQLEQPREHQQQQQHHQQQPEQPAQADNKDYAPSPAVLLQLTPSDWKNTQDKRNNWNRMQGMWGKRSQQQSDESALSEMTPPRMVKRAWSDLSQQGWGKRSWTQLHGVWGKRRWDQLHGAWGKRTPDQLEDDSKAEQPENSQEDEDQQSSSEVEREEANDSDDTVENSKRSGWNKMQGVWGKRSSSSSKTNSGPAIEGMGNNDLLLLISGTGDQL
  • Signal peptide:  MQFWQCPLLLMVSLIAAINT
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9GSK4-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000461_AF2.pdbhor000461_ESM.pdb

Physical Information

Mass: 133796 Formula: C53H72N14O17
Absent amino acids: CEFHIKMNPRTVY Common amino acids: QSW
pI: 3.75 Basic residues: 0
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: -87 Boman Index: -1427
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 49
Instability Index: 5986 Extinction Coefficient cystines: 11000
Absorbance 280nm: 1222.22

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones